ASSOCIATE DIRECTOR – IN VIVO PHARMACOLOGY Job at PharmaScouts
Are you experienced with in vivo pharmacology and would like to have the independence, resources, and support to lead a team and accomplish your goals? We are looking for a leader with good experience in rodent models of neurodegenerative diseases and/or neuroinflammatory diseases (systemic autoimmune and inflammatory diseases would be highly desirable). Our client is an early-stage biotech developing precision therapeutics for neurodegenerative, neuro-inflammatory, and immunological conditions with a pipeline of preclinical small molecule candidates. This unique company combines human genetics and AI-focused drug discovery to create novel, innovative therapeutics for patients who have little or no future hope.
In this role you will lead/mentor scientists who will be developing and executing in vivo strategies using a wide range of preclinical in vivo models (efficacy, PK/PD, screening toxicology etc). You will provide technical/scientific in vivo pharmacology expertise for a variety of drug discovery programs (target ID/validation to IND enabling studies).
Come be a critical part of the biology leadership team for this unique company where you can oversee the in vivo strategy (selection/development/validation of in vivo models).
Requirements:
- PhD (Immunology, Neuroscience, or other related)
- 6+ years in industry
- Expertise developing in vivo strategies and utilizing PK/PD/efficacy data to drive lead optimization and characterization of small molecule therapeutics
- Experienced in translational strategies to enable early clinical development
- Track record of scientific accomplishments (publications, patents, invited presentations)
- Excellent leadership and mentorship skills
- Hands-on experience with animal studies (including animal husbandry, IP, PO and subcutaneous dose administration, tissue harvesting, blood sampling)
Pluses:
- Experience with in vivo imaging and surgical procedures
- Familiarity with regulations and guidelines dealing with the humane use of animals in research
- Proficiency with GraphPad Prism
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